Prankishly teased about being sober (6)
I believe the answer is:
sedate
'being sober' is the definition.
('sedate' can be a synonym of 'sober')
'prankishly teased' is the wordplay.
'teased' can be anagrammed to 'SEDATE'.
Though, I'm unsure how this is indicated.
'about' acts as a link.
Can you help me to learn more?
(Other definitions for sedate that I've seen before include "Prim and proper" , "Give calming drug to" , "Calm, sober" , "Tranquilise" , "Not very exciting" .)