Primordial god inspires one Italian painter (6)
I believe the answer is:
titian
'italian painter' is the definition.
(I've seen this in another clue)
'primordial god inspires one' is the wordplay.
'primordial god' becomes 'titan' (I've seen this before).
'inspires' means one lot of letters goes inside another (inspire means to breathe in).
'one' becomes 'I' (Roman numeral).
'titan' placed around 'i' is 'TITIAN'.
(Other definitions for titian that I've seen before include "Venetian painter - shade of red" , "Venetian artist" , "Italian painter of the Venetian school, patronised by Philip II of Spain" , "painting" , "Reddish-gold; painter" .)