Produce Greene novel about Central London (8)
I believe the answer is:
engender
'produce' is the definition.
(I've seen this in another clue)
'greene novel about central london' is the wordplay.
'novel' indicates an anagram (letters in a new or novel order).
'about' is an insertion indicator.
'central' means to look at the middle letters.
The middle letters of 'london' are 'nd'.
'greene' anagrammed gives 'engeer'.
'engeer' placed around 'nd' is 'ENGENDER'.
(Other definitions for engender that I've seen before include "Generate - green den (anag)" , "Foment" , "Ned Green could breed" , "Produce or cause, emotions say" , "Give rise to (something)" .)