Railing as scientific establishment turned around American commerce (10)
I believe the answer is:
balustrade
'railing' is the definition.
(balustrade is a kind of railing)
'scientific establishment turned around american commerce' is the wordplay.
'scientific establishment' becomes 'lab' (I've seen this in other clues).
'turned' is a reversal indicator.
'around american' becomes 'us' (abbreviation for United States. I am not sure about the 'around' bit.).
'commerce' becomes 'trade' (trade is a kind of commerce).
'lab' back-to-front is 'bal'.
'bal'+'us'+'trade'='BALUSTRADE'
'as' is the link.
Can you help me to learn more?
(Other definitions for balustrade that I've seen before include "Parapet" , "feature of terrace, perhaps" , "Row of pillars under rail" , "Row of short pillars with coping" , "Handrail" .)