Raised grating voice finally in lament (5)
I believe the answer is:
dirge
'lament' is the definition.
(synonyms)
'raised grating voice finally' is the wordplay.
'raised' shows that the letters should be reversed in order (going up in a down clue).
'grating' becomes 'grid' (I've seen this in another clue).
'finally' indicates one should take the final letters.
The last letter of 'voice' is 'e'.
'grid' written backwards gives 'dirg'.
'dirg'+'e'='DIRGE'
'in' is the link.
(Other definitions for dirge that I've seen before include "Funeral song" , "Keen; lament" , "Dragging piece" , "Melancholy song" , "Elegy" .)