Raymond entertains non-drinker, irritable (5)
I believe the answer is:
ratty
'irritable' is the definition.
(I've seen this before)
'raymond entertains non-drinker' is the wordplay.
'raymond' becomes 'ray' (I've seen this in other clues).
'entertains' indicates putting letters inside.
'non drinker' becomes 'tt' (Teetotaller abbreviation).
'ray' placed around 'tt' is 'RATTY'.
(Other definitions for ratty that I've seen before include "describing vermin" , "Moley's friend" , "character on the river bank" , "Wretched" , "Short-tempered" .)