Restless craving (4)
I believe the answer is:
itch
'restless craving' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for itch that I've seen before include "Longing; anag. of 19" , "burn" , "Feel tingling sensation in skin" , "following seven years in union?" , "Hunger, longing" .)