River in the Rhine valley (4)
I believe the answer is:
neva
'river' is the definition.
(I know that Neva is a river)
'in the rhine valley' is the wordplay.
'in' indicates a hidden word.
'NEVA' can be found hidden inside 'rhine valley'.
(Other definitions for neva that I've seen before include "Woman" , "runner in St Petersburg" , "St Petersburg river" , "distant river" , "banker in Russia" .)