Run away from East European uprising (5)
I believe the answer is:
elope
'run away from' is the definition.
(thesaurus)
'east european uprising' is the wordplay.
'east' becomes 'E' (synonyms).
'european' becomes 'pole' (someone from Poland).
'uprising' says the letters should be written in reverse.
'e'+'pole'='epole'
'epole' written backwards gives 'ELOPE'.
(Other definitions for elope that I've seen before include "go off to the match?" , "Bolt" , "do a moonlight flit" , "Run away secretly to marry" , "Run away with lover" .)