Run over Bill in highway (4)
I believe the answer is:
road
'highway' is the definition.
(highway is a type of road)
'run over bill' is the wordplay.
'run' becomes 'r' (cricket abbreviation).
'over' becomes 'o' (cricket abbreviation).
'bill' becomes 'ad' (advertisement stuck on wall).
'r'+'o'+'ad'='ROAD'
'in' acts as a link.
(Other definitions for road that I've seen before include "public highway" , "For place to anchor" , "'The . . . . to hell is paved with good intentions'" , "Way to achieving a particular outcome" , "Parting guests used to take 'one for the --'" .)