Sanctuary of some uneasy luminaries (6)
I believe the answer is:
asylum
'sanctuary' is the definition.
(I know that sanctuary can be written as asylum)
'some uneasy luminaries' is the wordplay.
'some' indicates the answer is hidden within the clue (some parts of the word are used).
'ASYLUM' can be found hidden inside 'uneasy luminaries'.
'of' acts as a link.
(Other definitions for asylum that I've seen before include "Sanctuary or kind of hospital" , "Harbour" , "Institution for care of the insane" , "'Refuge, sanctuary (6)'" , "Haven or hospital for the mentally ill" .)