See way to cross Italian river (4)
I believe the answer is:
spot
'see' is the definition.
(thesaurus)
'way to cross italian river' is the wordplay.
'way' becomes 'st'.
'to cross' indicates putting letters inside.
'italian river' becomes 'po'.
'st' placed around 'po' is 'SPOT'.
(Other definitions for spot that I've seen before include "See; round mark" , "Notice; skin blemish" , "point on snooker table" , "Sight - site" , "Notice; sign of acne" .)