Setback concerning drinks for Speaker? (7)
I believe the answer is:
relapse
'setback' is the definition.
(I've seen this in another clue)
'concerning drinks for speaker?' is the wordplay.
'concerning' becomes 're' (both can mean on a particular topic).
'drinks' becomes 'laps' (lapping is a kind of drinking).
'for speaker?' indicates a 'sounds like' (homophone) clue (I've seen 'for speaker' mean this).
'laps' is a homophone of 'lapse'.
're'+'lapse'='RELAPSE'
(Other definitions for relapse that I've seen before include "Backslide as in health matters" , "Pleaser may slip to earlier state" , "Deteriorate in health" , "Fall ill again after rallying" , "New downturn in health" .)