Shame about end of true religious devotion (5)
I believe the answer is:
piety
'religious devotion' is the definition.
(I've seen this in another clue)
'shame about end of true' is the wordplay.
'shame' becomes 'pity' (synonyms).
'about' is an insertion indicator.
'end of' says to take the final letters.
The last letter of 'true' is 'e'.
'pity' enclosing 'e' is 'PIETY'.
(Other definitions for piety that I've seen before include "paying proper duty" , "Reverent quality" , "Religious feeling" , "Attentive religious practice" , "Quality of being religious" .)