She confuses the issue (5)
I believe the answer is:
susie
'she' is the definition.
'confuses the issue' is the wordplay.
'confuses' is an anagram indicator.
'issue' anagrammed gives 'SUSIE'.
(Other definitions for susie that I've seen before include "Woman" , "Girl" , "Girl's name" , "Wake Up Little - (Everly Brothers)" , "Little Susannah" .)