She's desperately sought in a Madonna movie (5)
I believe the answer is:
susan
'she's' is the definition.
'desperately sought in a madonna movie' is the wordplay.
I cannot quite see how this works, but
'a' could be 'an' and 'an' is located in the answer.
The remaining letters 'sus' is a valid word which might be clued in a way I don't understand.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for susan that I've seen before include "Girl's name; lazy -" , "Girl (sometimes lazy?)" , "Black-eyed -; lazy -" , "female" , "with blooming black eye?" .)