She's related new and extremely innovative chronicle (5)
I believe the answer is:
niece
'she's related new' is the definition.
I can't judge whether this defines the answer.
'and extremely innovative chronicle' is the wordplay.
'and' becomes 'n' (common abbreviation for 'and').
'extremely' suggests removing the centre (only the extremes of the word are used).
'chronicle' becomes 'ce' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'innovative' with its centre removed is 'ie'.
'n'+'ie'+'ce'='NIECE'
Can you help me to learn more?
(Other definitions for niece that I've seen before include "Son's cousin" , "Family girl" , "A younger female relative" , "Female family member" , "Brother's girl" .)