Shot to the face (5)
I believe the answer is:
botox
'shot to the face' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for botox that I've seen before include "(Temporary) anti-wrinkle treatment" , "Agent removing lines" , "poisonous cosmetic" , "It's used to smooth wrinkles, temporarily" .)