Should be driven with sufficient care (3)
I believe the answer is:
car
'care' is the definition.
(car care is a kind of care)
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for car that I've seen before include "Means of transport" , "Conveyance" , "Automobile" , "4-wheeled vehicle" , "Wheeled vehicle" .)