Sick of being fattened (3,2)
I believe the answer is:
fed up
'sick of' is the definition.
(synonyms)
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for fed up that I've seen before include "like infant in high chair?" , "Bored, browned off" , "Annoyed, bored" , "Hacked off" , "Disaffected" .)