Sleep in ghetto and live rough at first (7)
I believe the answer is:
slumber
'sleep' is the definition.
('slumber' can be a synonym of 'sleep')
'ghetto and live rough at first' is the wordplay.
'ghetto' becomes 'slum' (I've seen this before).
'and' says to put letters next to each other.
'live' becomes 'be' ('be' can be a synonym of 'live').
'at first' suggests taking the first letters.
The initial letter of 'rough' is 'r'.
'slum'+'be'+'r'='SLUMBER'
'in' acts as a link.
(Other definitions for slumber that I've seen before include "Sleep" , "The rest" , "Rumbles (anag.)" , "Overnight social event for (American) teenage girls" , "snores, maybe?" .)