Sloth, e.g. (3)
(Other definitions for sin that I've seen before include "Serious transgression" , "Immoral act" , "Misdeed" , "trip" , "Transgression of moral law" .)
I've seen this clue in the L.A. Times Daily, The New York Times, The Washington Post Sunday, the Wall Street Journal and The Washington Post.
I've seen this clue in The New York Times.
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