Snooker break is met with difficulty in the end (6)
I believe the answer is:
stymie
'snooker' is the definition.
(I've seen this before)
'break is met with difficulty in the end' is the wordplay.
'break' indicates anagramming the letters.
'with' is an insertion indicator.
'in the end' indicates one should take the final letters.
The last letter of 'difficulty' is 'y'.
'is'+'met'='ismet'
'ismet' is an anagram of 'stmie'.
'stmie' enclosing 'y' is 'STYMIE'.
(Other definitions for stymie that I've seen before include "Situation from which it is almost impossible to proceed" , "Block or thwart an activity" , "Prevent (by getting in the way)" , "Block; hinder" , "Snooker" .)