Some priest ran Georgia, leading to disunite (8)
I believe the answer is:
estrange
'to disunite' is the definition.
(thesaurus)
'some priest ran georgia leading' is the wordplay.
'some' indicates the answer is hidden within the clue (some parts of the word are used).
'ESTRANGE' is hidden within 'priest ran georgia leading'.
(Other definitions for estrange that I've seen before include "Reagents (anag.)" , "Make bad friends with sergeant" , "Drive away" , "Get cut off" , "Alien" .)