Some serenade leading singer (5)
I believe the answer is:
adele
'singer' is the definition.
(I've seen this before)
'some serenade leading' is the wordplay.
'some' indicates the answer is hidden within the clue (some of the parts of the word are used).
'ADELE' can be found hidden inside 'serenade leading'.
(Other definitions for adele that I've seen before include "Female English singer-songwriter, b. 1988" , "Popular female singer" , "Female singer from London" , "Singer with albums titled 19, 21 and 25" , "Performer" .)