Some sober up then throw up (5)
I believe the answer is:
erupt
'throw up' is the definition.
(thesaurus)
'some sober up then' is the wordplay.
'some' indicates a hidden word (some of the parts of the word are used).
'ERUPT' can be found hidden inside 'sober up then'.
(Other definitions for erupt that I've seen before include "Discharge" , "go up" , "Burst forth, like 25" , "Emit lava" , "What canines do" .)