Sound upset, drunk, staggering (10)
I believe the answer is:
stupendous
'staggering' is the definition.
(thesaurus)
'sound upset drunk' is the wordplay.
'drunk' indicates an anagram.
'sound'+'upset'='soundupset'
'soundupset' anagrammed gives 'STUPENDOUS'.
(Other definitions for stupendous that I've seen before include "Astounding" , "Extremely impressive" , "Phenomenal" , "Astoundingly huge" .)