Sour substance (4)
I believe the answer is:
acid
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">sour substance</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for acid that I've seen before include "Substance with pH of less than 7" , "Caustic and biting" , "Acerbic" , "- - -drop, sweet" , "Substance which turns litmus red" .)