Spice cocktail drunk up by second of two secretaries (7)
I believe the answer is:
paprika
'spice' is the definition.
(I've seen this before)
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for paprika that I've seen before include "Orange-red spice" , "Deep red spice" , "strong-tasting spice" , "Sweet red pepper" , "something spicy" .)