Spirit of writer transformed internally (4)
I believe the answer is:
brio
'spirit' is the definition.
(thesaurus)
I cannot understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for brio that I've seen before include "Dash or verve, from Italian" , "Spiritedness" , "Enthusiasm" , "'Liveliness, vivacity (4)'" , "Vigour (in music)" .)