Spirit suppressed by nudist, ill at ease (10)
I believe the answer is:
distillate
'spirit' is the definition.
(thesaurus)
'suppressed by nudist ill at ease' is the wordplay.
'suppressed by' indicates a hidden word.
'DISTILLATE' can be found hidden inside 'nudist ill at ease'.
(Other definitions for distillate that I've seen before include "Whisky, perhaps" , "Something produced by condensing vapour" .)