Spits blood and isolates? Not a problem! (5,2)
I believe the answer is:
loses it
'spits blood' is the definition.
(both can mean to become very angry)
'isolates? not a problem' is the wordplay.
'not' suggests deleting specific letters.
'problem' indicates anagramming the letters.
'isolates' with 'a' removed is 'isoltes'.
'isoltes' anagrammed gives 'LOSES IT'.
'and' acts as a link.
I've seen this clue in The Guardian.
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