Spleen, say, in newspaper? (5)
I believe the answer is:
organ
This clue is a double definition.
'spleen say' is the first definition.
(I know that spleen is a type of blood forming organ)
'newspaper?' is the second definition.
(organ can refer to a newspaper or journal)
'in' acts as a link.
(Other definitions for organ that I've seen before include "means for communicating information" , "Instrument with stops" , "Air-powered instrument" , "Body part - wind instrument" , "Medium; body part" .)