Standing up to the woman is a different thing (5)
I believe the answer is:
other
'a different thing' is the definition.
(thesaurus)
'standing up to the woman' is the wordplay.
'standing up' says the letters should be written in reverse (in a down clue up is reverse order).
'the woman' becomes 'her' ('her' refers to a woman).
'to' backwards is 'ot'.
'ot'+'her'='OTHER'
'is' is the link.
(Other definitions for other that I've seen before include "Not the one mentioned" , "Different; additional" , "Different (from those mentioned)" , "Alternate; additional" , "Alternative of two" .)