Suffer, with quite pained expression (5)
I believe the answer is:
allow
'suffer' is the definition.
(I know that suffer is a more specific form of allow)
'with quite pained expression' is the wordplay.
'with' is a charade indicator (letters next to each other).
'quite' becomes 'all' (I've seen this before).
'pained expression' becomes 'ow' (expression of pain).
'all' next to 'ow' is 'ALLOW'.
(Other definitions for allow that I've seen before include "Grant" , "Give leave to" , "Give permission to" , "brook" , "Permit or acknowledge" .)