Suffering in fact if led astray (9)
I believe the answer is:
afflicted
'suffering' is the definition.
(I've seen this before)
'fact if led astray' is the wordplay.
'astray' is an anagram indicator.
'fact'+'if'+'led'='factifled'
'factifled' with letters rearranged gives 'AFFLICTED'.
'in' is the link.
(Other definitions for afflicted that I've seen before include "Diseased; suffering" , "Caused pain to" , "Troubled" .)