Take point after cold caught in A&E (6)
I believe the answer is:
accept
'take' is the definition.
(synonyms)
'point after cold caught in ae' is the wordplay.
'point' becomes 'pt' (abbreviation for point).
'after' is a charade indicator (letters next to each other).
'cold' becomes 'c' (eg on taps).
'caught' becomes 'c' (cricket abbreviation).
'in' is an insertion indicator.
'c'+'c'='cc'
'cc' going within 'ae' is 'acce'.
'pt' after 'acce' is 'ACCEPT'.
(Other definitions for accept that I've seen before include "Receive what's offered" , "Acknowledge" , "Welcome" , "Admit into a group" , "Swallow" .)