Taken up in total, pot mixed with ecstasy (7)
I believe the answer is:
adopted
'taken up' is the definition.
('adopt' can be a synonym of 'take up')
'in total pot mixed with ecstasy' is the wordplay.
'in' means one lot of letters goes inside another.
'total' becomes 'add' (synonyms).
'mixed with' is an anagram indicator.
'ecstasy' becomes 'E' (informal term for the drug).
'pot' anagrammed with 'e' makes 'opte'.
'add' placed around 'opte' is 'ADOPTED'.
(Other definitions for adopted that I've seen before include "Taken as one's own" , "Chose to follow" , "raised issue on behalf of others" , "Took under one's wing" , "Fostered - assumed" .)