Tense to the end, large amounts missing (4)
I believe the answer is:
lost
'missing' is the definition.
(similar in meaning)
'tense to the end large amounts' is the wordplay.
'tense' becomes 't' (grammatical abbreviation).
'to' says to put letters next to each other (I've seen this in other clues).
'the end large amounts' becomes 'los' (I am not sure about this - if you are sure you should believe this answer much more).
't' after 'los' is 'LOST'.
Can you help me to learn more?
(Other definitions for lost that I've seen before include "Unable to find one's way" , "Not recognising one's whereabouts" , "Suffered defeat" , "Mislaid or strayed" , "Unable to find the way forward" .)