The last word in divine jam (11)
I believe the answer is:
predicament
'jam' is the definition.
(thesaurus)
'the last word in divine' is the wordplay.
'the last word' becomes 'amen' (last word in a prayer).
'in' is an insertion indicator.
'divine' becomes 'predict' (I've seen this in another clue).
'amen' inserted into 'predict' is 'PREDICAMENT'.
(Other definitions for predicament that I've seen before include "Quandary" , "Scrape" , "Spot" , "in corner" , "Difficult position" .)