"The Simpsons" teacher Krabappel (4)
I believe the answer is:
edna
'the simpsons teacher krabappel' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for edna that I've seen before include "- O'Brien, Ir. novelist" , "Female Dane, oddly" , "Famous dame" , "Dean (anag) - it's a girl's name!" , "Prolific Irish woman novelist . . . . O'Brien" .)