They oppose prayer losing intro? (5)
I believe the answer is:
antis
'they oppose' is the definition.
(I've seen this before)
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for antis that I've seen before include "People who are opposed" , "They're opposed to" , "Opponents" , "the group voting no" , "They say no" .)