Thus may be closed (4)
I believe the answer is:
shut
'closed' is the definition.
(I know that closed can be written as shut)
'thus may be' is the wordplay.
'may be' is an anagram indicator.
'thus' with letters rearranged gives 'SHUT'.
(Other definitions for shut that I've seen before include "Out of business" , "Close" , "See 19" , "Draw to" , "Closed" .)