Tide turns and no one is up -- that's the issue (7)
I believe the answer is:
edition
'the issue' is the definition.
(edition is a kind of issue)
'tide turns and no one is up' is the wordplay.
'turns' says the letters should be written backwards.
'and' is a charade indicator (letters next to each other).
'one' becomes 'i' (Roman numeral).
'is up' shows that the letters should be reversed in order (in down clue: letters go upwards).
'tide' back-to-front is 'edit'.
'no'+'i'='noi'
'noi' back-to-front is 'ion'.
'edit'+'ion'='EDITION'
'that's' is the link.
(Other definitions for edition that I've seen before include "I don tie (anag.)" , "Particular form of a book" , "(Copy from) single print run" , "Number of copies printed at one time" , "in printed form" .)