Times change, and things (5)
I believe the answer is:
items
'things' is the definition.
(I've seen this before)
'times change' is the wordplay.
'change' is an anagram indicator.
'times' is an anagram of 'ITEMS'.
'and' is the link.
(Other definitions for items that I've seen before include "Individual parts" , "partners" , "Individuals units" , "Elements" , "separate parts of news bulletin" .)