Tip-top line of approach causing confusion (6)
I believe the answer is:
tangle
'confusion' is the definition.
(I know that tangle is a type of perplexity)
'tip-top line of approach' is the wordplay.
'tip-top line of' becomes 't' (I can't justify this - if you can you should believe this answer much more).
'approach' becomes 'angle' (both can mean a way of looking at something).
't'+'angle'='TANGLE'
'causing' is the link.
Can you help me to learn more?
(Other definitions for tangle that I've seen before include "Seaweed; confusion" , "Twist together into a confusing mass" , "Complicated mess" , "A knotted mess" , "Confused mess" .)