Tired and sad chasing game woman ultimately (3-4)
I believe the answer is:
run-down
'tired' is the definition.
(I've seen this before)
'sad chasing game woman ultimately' is the wordplay.
'sad' becomes 'down' (down can mean sad or unhappy).
'chasing' means one lot of letters go next to another (some letters chase after others).
'game' becomes 'RU' (rugby union).
'ultimately' says to take the final letters.
The final letter of 'woman' is 'n'.
'ru'+'n'='run'
'down' put after 'run' is 'RUN-DOWN'.
'and' is the link.
(Other definitions for run-down that I've seen before include "In a neglected state" , "Shabby" , "Dilapidated" , "Worn-out" , "Exhausted" .)