Tired, worn out (5)
I believe the answer is:
jaded
This clue is a double definition.
'tired' is the first definition.
('jade' can be a synonym of 'tire')
'worn out' is the second definition.
('jade' can be a synonym of 'wear out')
(Other definitions for jaded that I've seen before include "Bored, sated" , "Bored, having had too much of something" , "Tired and bored, lacking zest" , "Weary from excess" , "Spent" .)