To play without interruption, use guesswork to some extent (5)
I believe the answer is:
segue
'to play without' is the definition.
I can't tell whether this definition defines the answer.
'interruption use guesswork to some extent' is the wordplay.
'to some extent' indicates a hidden word.
'SEGUE' is hidden within 'interruption use guesswork'.
Can you help me to learn more?
(Other definitions for segue that I've seen before include "Follow on seamlessly" , "Follow on without a pause" , "Follow smoothly on" , "Move between songs, etc, without a pause" , "Change smoothly from one thing to another" .)