Try small amount of LSD (4)
I believe the answer is:
stab
'try' is the definition.
(thesaurus)
'small amount of lsd' is the wordplay.
'small' becomes 's' (abbreviation - e.g. clothes size).
'amount of lsd' becomes 'tab' (I am not sure about this - if you are sure you should believe this answer much more).
's'+'tab'='STAB'
Can you help me to learn more?
(Other definitions for stab that I've seen before include "Rough guess; to knife" , "Wound with pointed weapon" , "Twinge; guess" , "Sudden sharp feeling" , "Puncture" .)